Acute Myeloid Leukemia ( Aml ) - 3312 Words

Acute myeloid leukemia (AML) is characterized by an increase in the number of myeloid cells in the marrow and an arrest in their maturation.(1) Make sure you use the ASM system for reference citation; I do not believe this format you have is correct. The symptoms of AML are caused by the replacement of normal bone marrow with leukemic cells, which causes a drop in red blood cells, platelets, and normal white blood cells.(2) These symptoms include fatigue, shortness of breath, easy bruising and bleeding, and increased risk of infection.(1) Several risk factors and chromosomal abnormalities have been identified. AML progresses rapidly and is typically fatal within weeks or months if left untreated. This disease is a heterogeneous clonal disorder of haemopoietic progenitor cells.(2) These cells lose the ability to differentiate normally and to respond to normal regulators of proliferation.(2) AML has a terrible prognosis, with only 23.8% of patients surviving five years after diagnos is. (3) AML is treated initially with chemotherapy aimed at inducing a remission; patients may go on to receive additional chemotherapy or a hematopoietic stem cell transplant. The majority of patients, despite reaching complete remission with classical chemotherapy, will relapse.(3) The persistence of malignant cells is what causes remission. (3) Acute myeloid leukemia affects both older and younger patients. However, most patients are older than 60 years old, and the prognosis is worse forShow MoreRelatedCase Study : Acute Myeloid Leukemia1003 Words   |  5 Pages Case Study: Acute Myeloid Leukemia Niki Lovelace Middle Tennessee State University Advanced Pathophysiology NURS 5103 R58/Spring 17 20 February 2017 Introduction S.L. is a 34-year-old male that arrived at his primary care provider’s office today for what he states is his fourth â€Å"cold† this year. He proclaims that he has been coughing non-stop and feels congested. He denies taking his temperature but has felt occasional sweats and chills. This being his fourth visit to his primaryRead MoreAcute Myeloid Leukemi Symptoms And Treatment1866 Words   |  8 PagesConnor Stockman Bio 325 12/2/14 Acute Myeloid Leukemia This year in the United States there will be an estimated 1,665,540 diagnosed cancer cases and 585,720 deaths due to the disease.1 Cancer ranks as the second most common cause of death in the US only behind heart disease. As cancer accounts for nearly a quarter of all deaths in the United States2, many people view the diagnosis of cancer as a death sentence. This feeling of hopelessness can lead patients to make questionable decisions regardingRead MoreDiagnosis And Classification Of Myeloproliferative And Myelodysplastic Disorders1678 Words   |  7 Pagescell types of the myeloid lineage, including erythroid, granulocytic, monocytic, or megakaryocytic lineages. These disorders are clonal and originate from a single pluripotent hemapoietic stem cell (Hubbard, 2011). MPNs have a slow onset and are mainly diagnosed in adults between 45 and 55 years of age. Clinical symptoms include anemia, weight loss, lack of energy, spleen enlargement, fever, and bruising (Hubbard, 2011). The major diagnostic criterion for chronic myelogenous leukemia (CML) is the presenceRead MoreDoes Down Syndrome Increase the Chances of Developing Leukemia?1098 Words   |  5 Pagessyndrome is a genetic disease that occurs in people that have 47 chromosomes instead of 46. Does the Down syndrome increase the chances of developing leukemia? What health risks are involved in trying to keep children from getting leukemia? I have personally seen the effects of Down syndrome. There have been clinical trials that have shown the results of leukemia on kids with Down syndrome. The life expectancy has gone up dramatically because of medicine. Down syndrome has affected the lives of many andRead MoreAcute Panmyelosis With Myelofibrosis ( Apmf )1688 Words   |  7 PagesAcute Panmyelosis with Myelofibrosis (APMF) is a rare type of acute myeloid leukemia that manifests with a rapidly fibrotic bone marrow and progressive cytopenias. APMF is usually fatal, a consequence of the disease’s ubiquitous pathologic and disease features, rapidly progressive course, and poor response to traditional treatments. The disease is pathologically recognized for its heavily fibrotic marrow, increased overall cellularity, immaturity of all cell line lineages, abnormal megakaryocyteRead MoreThe Genetic And Clinical Risk Factors For Explosion Phase Progression Of Chronic Leukemia1922 Words   |  8 PagesIntroduction The myeloproliferative neoplasms carry an inherent risk of transformation to an accelerated-phase disease, as well as ultimately to acute leukemia. The likelihood of disease evolution is mitigated by various clinical, biological and genetic factors, as well as the by the underlying initial MPN diagnosis. Here we review the genetic and clinical risk factors for blast-phase progression of chronic-phase Phliadelphia-chromosome negative MPNs, as well as therapeutic outcomes to date. WeRead MoreAn Evaluation Of The Nih Clinical Trial Registry1777 Words   |  8 Pagespost-HSCT supportive care2,3. HSCT is a potential curative treatment for a number of malignant hematologic diseases such as myelodysplastic syndrome (MDS), leukemia, lymphoma and myeloma which tend to more commonly affect the elderly population. For instance, according to the SEER database, the median age of diagnosis of acute myeloid leukemia (AML) and MDS are 67 and 70 years respectively. Despite these findings, the number of patients over the age of 65 undergoing allogeneic HSCT remains low4. AnRead MoreThe Four Main Types Of Blood Cancers814 Words   |  4 Pagescancers: acute myeloid leukemia (AML), chronic myeloid leukemia (CML), acute lymphocytic leukemia (ALL), and chronic lymphocytic leukemia (CLL). AML and ALL can become fatal within in a few weeks or month if not properly treated. CML and CLL has a slower progression rate than there chronic counterparts. Patients with AML or ALL tend to have noticeable symptoms whereas patients with CML or CLL tend to be asymptomatic (Hallek, 2015). Even though chronic leukemia progresses slowly, acute leukemia is easierRead MoreEssay on Leukemia: Cancer of the Blood1639 Words   |  7 Pagespicks up wastes from the cells for delivery to the urinary organs. These functions could not be provided for the individual cells without the blood. Like any other structure of the body, blood can be attacked by many types of disease, such as Leukemia. Leukemia is a g eneral name given to a number of blood cancers that affect the blood. Blood transports hormones, enzymes, buffers, other types of biochemicals that are important in body functions. The blood is made of plasma and formed elements. PlasmaRead MoreToo Many Diagnosed with Leukemia1325 Words   |  5 Pagesestimated 31,000 new diagnosis of leukemia (Gould Dyer, 2011). Leukemia is a cancer of the white blood cells. Bone marrow the spongy tissue inside the bone is where the blood cells are made (The Leukemia Lymphoma Society). Normal white blood cells fight infections in our bodies. In leukemia, the bone marrow is making abnormal white blood cells. The two main types of white blood cells that leukemia affects are; lymphocytes and myeloid cells (The Leukemia Lymphoma Society). Lymphoblasts are